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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications originally developed for managing type 2 diabetes mellitus, though some are now also licensed for weight management in individuals with obesity

Data from Phase 2 trials (NEJM, 2023) indicate that these effects are generally mild to moderate and transient

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NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway

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