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Immediate medical review is necessary for these signs, and therapy should be paused until a clinician evaluates the cause

A thin layer of 1% hydrocortisone cream applied to the injection site reduces both itching and inflammation

These locations were selected because they provide adequate subcutaneous tissue depth for reliable absorption, easy access for self-administration, and relatively low risk of hitting blood vessels or nerves

Further studies indicate that TA-III causes mitochondrial damage and excessive ROS production by increasing intracellular fat phagocytosis and promoting the production of free fatty acids (FFA), which eventually lead to cell damage and even death

Continued Treatment With Tirzepatide for Maintenance of Weight Reduction (SURMOUNT-4)