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261, 262 Although high rates of efficacy were reported (47 to 64%), given the extremely small combined sample size of fewer than 30 patients, the relatively serious AEs (e.g., new diabetes onset, exacerbation of existing diabetes, pneumonia with septic shock, increased blood pressure), and the known risks of systemic long-term glucorticoid use, risks/burdens clearly outweigh benefits and the Panel recommends that this therapy not be used long-term

Common Appearances of Semaglutide Semaglutide is a medication used to help control blood sugar levels in people with type 2 diabetes and to assist in weight management

A., Costello, M

The side effect profiles differ somewhat between the two molecules, though both cause gastrointestinal symptoms as their most common adverse effects

3 This is known as the rebound effect