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Guenther LM, Dharia NV, Ross L, Conway A, Robichaud AL, Catlett JL 2nd, et al
After having lost a mean of 17.3% of their bodyweight on semaglutide and 2.0% on placebo at 68 weeks, they regained 11.6% and 1.9% of weight, resulting in net losses of 5.6% and 0.1% at week 120
Furthermore, a 2018 study using NHANES data modeled the impact of obesity on mortality improvement between 1988 and 2011 and found that rising BMI levels reduced mortality improvement in the US by more than 0.5% per annum
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