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Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalian cells

Large randomized trials that were previously conducted indicated that 3453% of participants were not able to achieve an HbA1c of less than 7% through AID treatment, primarily due to suboptimal postprandial glucose control

However, this effect may be due to the large amount of cystine provided in the control conditions (208 M), as reduction of cystine levels in the medium did not impair growth but abolished intracellular cysteine and cystine levels (Extended Data Fig

Chronic hypoxia suppresses pregnancy-induced upregulation of large-conductance Ca2+-activated K+ channel activity in uterine arteries

doi: 10.1001/archinternmed.2008.574 56