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Overlay of non-transformed metabolomics pixel array and ST cell centroids showing spatial discrepancy
Human orthologs of FFAR2 have similar affinity for acetate and propionate followed by butyrate, while FFAR3 has higher affinity for propionate and butyrate compared to acetate (68)
Both share TB-500 (10mg) as a shared actin-regulation component
You can read the abstract of this article at 679-P: The Novel GIP, GLP-1, and Glucagon Triple Receptor Agonist LY3437943 Exhibits Robust Efficacy in Preclinical Models of Obesity and Diabetes | Diabetes | American Diabetes Association (diabetesjournals.org)
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