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8.4 Pediatric Use Safety and effectiveness in the pediatric population have not been established [see Boxed Warning, Warnings and Precautions (5.1)]
Retatrutide has shown strong weight loss results in early research, with people losing an average of 28.7% of their body weight over roughly 68 weeks at the highest studied dose
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Chronic systemic inflammation is a feature of insulin resistance and diabetes, possibly as an effect but with some suggestion that it may actually be causative (Vondra 2021
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