You should contact your GP urgently if you experience: Bleeding so heavy that you soak through your usual sanitary protection every hour for several consecutive hours Passing large blood clots repeatedly Bleeding between periods or after intercourse Symptoms of anaemia, including persistent fatigue, breathlessness, palpitations, or dizziness Pelvic pain or pressure that is new or worsening Any postmenopausal bleeding (bleeding occurring 12 months or more after your last period) Seek immediate medical attention (attend A&E or call 999) if you experience severe bleeding accompanied by signs of haemodynamic compromise, such as feeling faint, confusion, rapid heartbeat, or cold and clammy skin
Dose escalation timeline The standard tirzepatide dose escalation moves from 2.5 mg to 5 mg after 4 weeks, then to 7.5 mg after another 4 weeks, then to 10 mg, potentially up to 15 mg
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Science 383 , 830832 (2024)
Wanders, Biochem