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Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/-catenin pathway to aggravate stemness, proliferation, migration and invasion in papillary thyroid carcinoma
receiving grant support from Merck Sharp & Dohme
Cyclic Lactam Structure and Receptor Engagement MT-2s cyclic lactam structure formed by a bridge between Lys and Asp residues in the parent -MSH sequence locks the peptide into a conformation that maintains the critical His-Phe-Arg-Trp pharmacophore in an orientation that enables high-affinity binding across multiple melanocortin receptor subtypes
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Armstrong RN (1991)
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