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Compared to usual care, GLP-1RA use was associated with a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions
Insurers are basing their coverage decisions, in part, on rebates, discounts that are offered by drugmakers as a negotiating chip to persuade insurers to cover one product over a competitor
The piece was updated in November 2025
Available from www.who.int/mediacentre/factsheets/fs311/en/
How GLP-1 Medications Work Learn how these medications curb appetite, stabilize blood sugar, and support weight loss
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