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Moreover, ferroptosis can propagate through intercellular mechanisms involving the release of damage-associated molecular patterns (DAMPs), dysregulation of immune checkpoints, and exosome-mediated signaling, collectively driving microglial activation, T-cell infiltration, and bloodbrain barrier disruption, culminating in systemic immune imbalance
De Silva N, Samblas M, Martnez JA, Milagro FI
The electron donation can affect the receiving molecule in varying ways including neutralizing reactive oxygen species, or maintaining cysteine in proteins in their reduced forms
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