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These factors, as well as obesity-related leptin resistance, were shown to have somnogenic activity
For years, doctors dismissed these patients as anxious or overreacting
The levels of incretins including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic hormone rise in response to a meal, and they are rapidly degraded by the enzyme dipeptidyl peptidase 4 (DPP-4) [5]
And finally, GLP-1 slows gastric emptying , prolonging the feeling of fullness until the next meal
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