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Results Gpx1 deficiency protects from Con A-induced liver injury To investigate the role of Gpx1 in experimental T cell-mediated hepatitis, we injected Con A into WT and Gpx1 KO mice
Low GSH, neutrophil infiltration, myeloperoxidase activity and inflammation increase oxidative stress overwhelming the antioxidant defense, and hypochlorous acid mediated GSH oxidation and its attachment to proteins contribute to further GSH deficiency (114)
The apparent differences between rodents and primates may reflect differences in blood-brain barrier permeability across species (319)
Sulfur is sticky, so toxins and free radicals adhere to it
Li et al., 2021b
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