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Food and Drug Administration or the European Medicines Agency for any indication

The oral bioavailability question remains somewhat controversial

Additionally, BH4 is involved in CoQ10 synthesis, an important lipophilic antioxidant that captures and neutralizes lipid peroxidation radicals, protecting membrane phospholipids, especially those with two PUFA tails, from oxidative degradation (Gu et al., 2023)

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