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Lorenzo Leggio, a National Institute on Drug Abuse clinical director who wasn't involved in the study

The ROS generation was detected with a Leica fluorescence microscope (Leica DM6000B) using Leica LAS X software, and quantitative analysis was performed with ImageJ software (version 1.60

inheritance of this mutant in hemizygotes is expected to cause embryonic lethality

These logistics are manageable but represent a real difference in daily treatment burden between an oral pill and an injectable biologic