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Hurd TR, Collins Y, Abakumova I et al (2012) Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species

"Discoloration of skin and urine after treatment with hydroxocobalamin for cyanide poisoning"

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Additionally, Chang et al (110) demonstrated that exenatide exerted cardioprotective effects against oxidative stress-induced injury both in vitro and in vivo, which was potentially attributed to the clearance of oxidative stress products (such as ROS), increased concentrations of antioxidant defense enzymes and suppression of myocardial cell apoptosis

So, GLP-1 agonist users must incorporate other weight loss and maintenance tactics, such as exercise and adopting healthy behaviors to help maintain weight loss after taking the drug