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421 Notably, dotinurad has demonstrated safety in patients with an estimated glomerular filtration rate (eGFR) between 60 ml/min and 30 ml/min, without necessitating any dosage adjustments
As previously reported, firsocostat and cilofexor alone or in various two-drug combinations with the ASK1 inhibitor selonsertib (GS-4997) failed to significantly increase the likelihood of fibrosis improvement without worsening NASH
J Clin Endocrinol Metab 90(4):19291935
2018;28(8):919924
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