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In particular, topiramate may control the flow of glutamate and cysteine through System Xc-, which could impact GSH synthesis and improve the ability of GPX4 to change harmful lipid hydroperoxides into safe lipid alcohols

for example, isoniazid, cycloserine, penicillamine, and hydralazine each form complexes with B or otherwise interfere with B metabolism, potentially leading to deficiency and peripheral neuropathy

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