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UPR activation is particularly prominent in active MS lesions, driven by increased levels of inflammatory cytokines, reactive nitrogen species (RNS), and ROS
If GLP-1 therapy turns down one volume knob on the brains hunger signal, cagrilintide turns down a different, parallel volume knob
Asian J Androl 16:3138
& Bergad, C
These milestones highlight the growing regulatory and clinical momentum supporting expanded uses Ongoing trials are also exploring the impact of GLP-1 agonists on cardiovascular outcomes, liver health, and even neurodegenerative diseases, reinforcing their value in treating systemic metabolic disorders
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