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It also regulates Th17 and Treg cell proportions in mesenteric lymph nodes and modulates IL-17A and Foxp3 expression in the colon, aiding in Th17/Treg balance recovery
Later, the same research team found that keratinocyte-specific knockout mice lacking GPX4 showed aberrant epidermis proliferation, infiltration of inflammatory cells in the dermis, and morphologic alteration of hair follicles
While many of these studies are based on animal models, early human trials and anecdotal reports suggest promising results
While controlled clinical trials are limited, anecdotal and preliminary data suggest multiple benefits: Skin Rejuvenation: Many patients notice firmer, smoother skin after treatment
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