In a yearlong Phase 3 trial, the highest dose of Lilys pill, orforglipron, lowered a measure of blood sugar called A1C by 1.9 percentage points, while the highest dose of Novos drug, marketed as Rybelsus, lowered A1C by 1.5 percentage points, when analyzing all patients regardless of discontinuations
While clinical trial data supports its efficacy, adoption is still limited to tier-1 cities and private healthcare setups due to its premium pricing
Patients can reach out for assistance if they suspect issues with their medications.
Compounded versions, including those with glycine, are prepared by pharmacies under their own quality standards and are legal when prepared by licensed pharmacies with valid prescriptions
Adverse effects were uncommon and mild (10 patients) and resolved after discontinuation