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Tirzepatide is not a hormone replacement therapy but influences metabolic hormones indirectly through its dual GIP/GLP-1 receptor actions, improving insulin secretion, reducing glucagon, and affecting appetite-regulating pathways

I'm doing research on the GLP-1 connection with papillary right now, because I see patients with thyroid cancer who have obesity and they're at high risk for recurrent thyroid cancer

The dual-targeting nature of tirzepatide makes it more complex to replicate, especially maintaining the same activity and stability, key for FDA biosimilar approval

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