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A substudy of this phase 1b trial showed also that retatrutide delays gastric emptying in humans, as measured by the acetaminophen test, though this effect lessens over time due to tachyphylaxis [44]
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Some patients may require an even higher dose of 2 mg weekly for optimal effect, particularly for weight management indications, though this should be approached cautiously with careful monitoring for adverse effects
You should consider a form of backup contraception for a short time
And we are not fully clear on specific mechanisms, like the black box, or potential side effects and downsides, Dillon said
