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Psychological Causes Depression and anxiety

doi: 10.1371/journal.pgph.0005516

However, the benefit in reducing stroke events was not seen in the outcome studies of SGLT-2 inhibitors (260)

Many describe the effect as similar to having an internal gastric band, since portions shrink and cravings, especially for calorie-dense foods, become less intense

(And if they did tell us what diets, if any, were prescribed, whether or not the patient complied with the dietary prescription might itself be a confounder in interpreting any associations observed.) Ultimately to know which is safer and more effective in a diet vs drug comparison, which approach has the greatest benefit-to-risk ratio for all these numerous chronic disorders, clinical trials comparing the two are necessary