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For example, signaling through the chemokine receptor, CCR2, or Fc receptor promote inflammation through upregulation of the IL-6 pathway, leading to activation of signal transducer and activator of transcription 3 (STAT3) by ischemic endothelium (Arbaizar-Rovirosa et al., 2023)

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It is often used when a patient has a specific allergy to a dye or preservative in a commercial drug, or when a patient requires a liquid version of a medication that only comes in pill form