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Preferential tissue distribution to kidneys, liver, and gastrointestinal tract aligns with observed therapeutic effects in animal studies

Animal studies have failed to establish a lethal dose even at concentrations thousands of times above therapeutic levels

Poor dietary intake of B12-rich foods, such as meat, fish, and dairy products, is one of the most common causes of vitamin B12 deficiency

Needle sizing follows a flipped scale: a higher gauge number actually means a narrower shaft, so a 25-gauge needle is finer than a 21-gauge one