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Lantus (insulin glargine), Sanofis long-acting insulin, became the subject of a Congressional investigation in 2021 after its list price increased more than tenfold over 15 years while the company accumulated formulation and device patents to block biosimilar entry
10.1016/j.bbr.2009.06.035 248
NichollsSJBhattDLBuseJBPratoSDKahnSELincoffAMet alComparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics
There's not any one specific factor that we know of, or that has been studied, to say, These are the patients who are being extremely successful at maintaining weight loss versus not being successful, says Simonetti
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