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Rachele explains that Glutathione production can naturally decline with age, and it can also be depleted by chronic stress exposure to pollution a poor diet When levels drop, oxidative stress may increase and the body can become more vulnerable to inflammation, fatigue and slower recovery

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In short-term experiments, it was observed that KA did not affect granule cells in monolayer cultures of fetal rat cerebellum but showed cytotoxic effects on Purkinje neurons [117]