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For weight management, the proportion of individuals with overweight or obesity achieving 5% weight loss increases (approximately equivalent to 25 kg, depending on baseline weight), a threshold associated with improvements in blood pressure, blood lipids, functional capacity, and health-related quality of life 48

An extra portion of vegetables, higher-quality protein, or seasonal fruit provides far more benefit than expensive multivitamins

Shared decision-making between patients and clinicians should weigh cardiovascular benefits against cost, adverse effects, and individual treatment goals

Travel situations often prompt temporary switches from injection to nasal spray

MC3R, energy and inflammation MC3R is expressed mainly in the central nervous system and on immune cells