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On the contrary, in adult male rats treated with 25 g/kg/week AFB1 for 8 weeks, AFB1 could trigger obvious neurotoxicity, inflammatory responses, oxidative stress and, anxiety and depression-like behaviors (241)

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In contrast to IL-10, tumor necrosis factor induced protein 3 (TNFAIP3), also known as an anti-inflammatory protein (43), was already downregulated at 24 h and reached again the initial level at 14 d pi

Materials and Methods Cell culture and reagents Dissociated cortical neuron cultures from Sprague-Dawley rats were prepared as described previously (62)