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NNMT is expressed abundantly in adipose tissue, where it has been associated with fat cell size and lipid storage dynamics

That slowdown helps you feel fuller on less food for longer, but when food lingers in the stomach, it can also "cause a lot of gastrointestinal effects, like nausea, indigestion and other GI issues," says Dr

J Physiol 587(19):47494759 Hlscher C (2014) Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

Introduce healthy fats more deliberately

Microdosing GLP-1 agonists involves taking a smaller-than-prescribed dose of the medication to experience some of its benefits, while potentially reducing side effects