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The GLP-1 medications work primarily in the brain, obesity medicine physician-scientist Dr
placebo), most of them (liraglutide, semaglutide SC, dulaglutide, albiglutide, and efpeglenatide) have also demonstrated a reduction in MACE with respect to placebo, while weekly exenatide or oral semaglutide showed a tendency to reduce MACE
However, its precursor TMA has a negative effect on bloodbrain barrier function [247]
Continued coordination and thoughtful policy design will be essential to ensuring that members can benefit from innovations like GLP-1s without compromising the long-term sustainability of our plans
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