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The reason injectable GLP-1 drugs like semaglutide and liraglutide work is that they are chemically modified versions of the hormone
Audrey Moreau LG, Kahina Belhous, Gerald Franchi, Vincent Couloigner, Jerome Nevoux, Pierre Antoine Aymard, Arnaud Picard, Veronique Minard-Colin, Natacha Kadlub
Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: A randomized controlled trial
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To be clear, the motivation for weight loss in obesity is not cosmetic
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