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However, modest decreases in glucose, insulin, and HOMA-IR (homeostatic model assessment for insulin resistance) did not reach statistical significance (183)

doi:10.5114/reum.2016.64911 Hfling DB, Chavantes MC, Juliano AG, et al

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Several lifestyle factors can be adjusted to help reduce the appearance of dark circles, as highlighted in Dr Zoya Diwans recent Good Housekeeping Article(LINK), including getting more sleep, increasing your fatty acid intake and using illuminating concealers