Most notably [1, 12]: Hypoglycemia Hypoglycemic events are occasionally observed in GLP-1-RA use and are positively linked with concomitant use of other antidiabetic drugs
[1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma)
MeseguerSNavarro-GonzlezCPanaderoJVillarroyaMBoutoualRSnchez-AlczarJAet al
The drugs have produced game-changing results in treating type 2 diabetes and obesity, both of which are strongly linked to cardiovascular disease, metabolic disorders, and numerous other chronic diseases
Sci Adv 6:eaay9751 Hamilton EP, Ma C, De Laurentiis M, Iwata H, Hurvitz SA, Wander SA et al (2024) VERITAC-2: a phase III study of vepdegestrant, a PROTAC ER degrader, versus fulvestrant in ER+/HER2-advanced breast cancer