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For PWS patients, GLP-1 therapy represents a novel pharmacological approach that addresses the root neurobiological cause of hyperphagia rather than simply restricting calorie intake
Even with a letter of medical necessity, most administrators will still deny reimbursement
It directly inhibits tyrosinase, the enzyme responsible for converting tyrosine into melanin, by binding to copper ions at the enzymes active site
Theres no statutory requirement for training before someone administers it, which the Joint Council for Cosmetic Practitioners has flagged as a specific gap it wants closed
These side effects can persist for several days and may affect more than one in 10 patients
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