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It is often the dose, timing, and stacking
These proteins clear neurotransmitters from the synapse
PMC 8999041
A 1,000-microgram tablet would be expected to result in a 10 to 20-microgram dose
57-59 Brain Atrophy Patients with depression have consistently been found to have substantial reductions in volumes of the hippocampus (part of the limbic system) and medial prefrontal cortex regions of the brain, affecting both emotional regulation and cognition
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