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at worst, the same antibodies can elicit life-threatening complications, possibly even systemic anaphylaxis.16 17 Carcinogenicity Carcinogenicity is the ability of a substance to cause cancer

Foy and Furman, 1972

The upregulation of interferon-stimulated gene 15 in TECs disrupted mitochondrial homeostasis and triggered the release of mtDNA into the cytosol, which then triggers NLRP3mediated pyroptosis in cyclic GMP-AMP synthase-stimulator of interferon genes pathway (47)

Therefore, we recommend the use of stably transfected cells for experimental data acquisition, while transiently transfected cells can be used to verify targeting of specific organelles by different sensors

However, more research is needed to support these claims