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Yes, semaglutide is itself a peptide (a GLP-1 receptor agonist)

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Current evidence suggests that the long-term safety profile of GLP-1 receptor agonists is favorable for most patients who tolerate therapy during the early phases of treatment

Start your intake How Semaglutide Supports Kidney Function in CKD Semaglutide works through GLP-1 receptors found throughout the body, including in kidney tissue

Implication for cytotoxicity