This gastric slowing can also affect the absorption of some oral medications, particularly with tirzepatide, which can reduce the effectiveness of oral contraceptives
Front Endocrinol (Lausanne) 12 , Liu, X., Patel, K
In non-diabetic mice, GLP-1 infusion increased GFR by reducing preglomerular resistance [20], an observation that could potentially explain the physiological increase in GFR observed in the postprandial compared to the fasting state, although human studies infusing GLP-1 peptide could not replicate this observation [21]
Pain is the biggest symptom: Patients often describe menstrual pain that's worse than what others with periods experience, as well as pain that gets worse over time
On the surface, it seems like a minor chemical substitution