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Clinical trials in people with type 2 diabetes and CKD have shown potential kidney benefits with semaglutide, though this is not a licensed renal indication in the UK

How Semaglutide Targets the Brain Hunger System Semaglutide functions as a GLP-1 receptor agonist, meaning it binds to GLP-1 receptors located throughout the brain's appetite-control centers, including the hypothalamus and brainstem

But it can also come with an unwelcome side effect: diarrhea

However, semaglutide does not significantly reduce the risk of non-fatal stroke and hospitalizations (for angina and heart failure), warranting caution when interpreting its overall benefit

Consult your prescriber before making any changes