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Adding semaglutide to retatrutide would duplicate GLP-1 receptor activation, which could increase side effects without proportionally increasing efficacy

doi: 10.1016/j.aorn.2010.04.015 18 SinghiADPaiRKKantJABartholowTLZehHJLeeKKet al

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doi: 10.3390/antiox8120637 152 SepidarkishMAkbari-FakhrabadiMDaneshzadEYavariMRezaeinejadMMorvaridzadehMet al