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The aims of this study were to identify biomarkers that precisely reflect visual field defects and the loss of RGCs in human subjects, and to identify IOP-independent biomarkers of glaucoma in a validation study based on targeted metabolomics

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Research suggests that Akt-mediated eNOS phosphorylation may increase nitric oxide (NO) bioavailability within vascular tissue microenvironments, potentially supporting vasodilation, microvascular integrity, and organized angiogenic responses in tissues with limited baseline vascular supply such as tendon, ligament, and fibrocartilaginous structures

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Stanford, J