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SASP (senescence-associated secretory phenotype) results revealed that FOXO4-DRI downregulates the levels of IL-1 , IL-6 , IL-8 , and TNF- (Figure 4H)

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GLP-1 appears to modulate inflammatory pathways and reduce intracranial pressure through direct actions on the choroid plexus in the context of migraine and IIH [23,24,25]

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