10.18632/oncotarget.16219 193 WangJ.-L.LiuB.ZhangC.WangX.-M.ZhenD.HuangX.-M.et al (2019)
Research published in eBioMedicine confirmed that cagrilintide lowers body weight specifically through brain amylin receptors 1 and 3 (AMY1R and AMY3R), and these are distinct from the receptors that GLP-1 agonists activate
Rapid acetylators were competent in isoniazid acetylation but the drug was cleared less efficiently in the slow acetylator group, which resulted in elevated serum concentration and led to adverse neurologic side effects due to an accumulation of unmetabolized drug (Brockton et al., 2000)
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