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Altschul, S

These first-generation compounds established the foundational research framework for incretin-based metabolic studies

Measurements were validated using the Wave software (Agilent, Santa Clara, California, USA) and normalized to DNA concentrations per well, analyzed in stained cells (Hoechst 33342) using a plate reader (Tecan Infinite M200, Tecan Group Ltd., Mnnedorf, Switzerland) with an excitation wavelength of 350 nm and an emission wavelength of 461 nm

PCAC member Elizabeth Rebello, a professor in the Department of Anesthesiology and Perioperative Medicine at the University of Texas MD Anderson Cancer Center, cited the "lack of efficacy data and randomized controlled trials" as her basis for her no vote

Additional Sources: Westchester Medical Center Health: Beyond the Ozempic Buzz: How GLP-1s Actually Work National Academy of Medicine: GLP-1 Key Facts Baylor Scott and White Health: GLP-1 medications explained: Benefits, risks and how they work National Kidney Foundation: GLP-1 Receptor Agonists (GLP-1 RAs)