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If you are already succeeding on liraglutide with good tolerance and satisfactory weight loss, the disruption of switching may not be worth it

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A study published in Circulation noted that while these reductions in muscle volume appear proportionate to the weight loss achieved, the concern remains that excessive lean mass loss could lead to sarcopenia, reduced metabolic rate, and poorer long-term outcomes

This is up to five times the normal energy use than if they had not been removed, which uses up their energy stores unnecessarily