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The observational nature of our data precluded inference of causality, which might be confirmed in future research, such as in ongoing randomized controlled trials evaluating the efficacy of tirzepatide in improving CV and kidney outcomes compared with GLP-1 agonists and in treating patients with heart failure with preserved ejection fraction.

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That matters even more when a person is using a GLP-1 medication and already noticing changes in appetite or digestion