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It reduces succinic semialdehyde (SSA), a product of gamma-aminobutyric acid (GABA) catabolism, to 4-hydroxybutyric acid (Fig

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CL int is calculated from the first-order depletion rate constant (k), derived from the slope of the ln(% remaining) versus time plot

The medications have skyrocketed in price and popularity, but they're now being blamed for crippling budgets in the public and private sector