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Nrf2 is controlled by two distinct -TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
Grynkiewicz, G., Poenie, M
In the blood and other cells in the body GSH works to eliminate compounds that are either from outside the body or metabolites that need to be excreted
11 , dmm034212 (2018)
This includes DNA from infecting microbial genomes, 95 DNA generated through the reverse transcription of viral RNA, 96 and even host DNA that escapes into the cytoplasm due to DNA damage or compromised nuclear or mitochondrial membranes
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